A self-calibrating PARACEST MRI contrast agent that detects esterase enzyme activity
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چکیده
منابع مشابه
A self-calibrating PARACEST MRI contrast agent that detects esterase enzyme activity.
The CEST effect of many PARACEST MRI contrast agents changes in response to a molecular biomarker. However, other molecular biomarkers or environmental factors can influence CEST, so that a change in CEST is not conclusive proof for detecting the biomarker. To overcome this problem, a second control CEST effect may be included in the same PARACEST agent, which is responsive to all factors that ...
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ژورنال
عنوان ژورنال: Contrast Media & Molecular Imaging
سال: 2010
ISSN: 1555-4309
DOI: 10.1002/cmmi.421